HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0034605 - cellular response to heat
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 505
+	Hs
		437833 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431463 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Rn
		581936 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HS90B_RAT (1-504): 0: 673: 70.11
+	Rn
		94158 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HS90B_RAT (1-504): 0: 673: 70.11
+	Rn
		581980 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HS90A_RAT (1-504): 0: 654: 61.98
+	Rn
		94203 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HS90A_RAT (1-504): 0: 654: 61.98
+	Hs
		496215 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Hs
		431504 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		438364 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		HS90B_HUMAN (1-504): 0: 671: 69.93