HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CE350 (Q5VT06)
Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa)
Gene: CEP350

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008017 - microtubule binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 3117
+	Hs
		497051 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLEC_HUMAN (1444-2943): 4.71e-31: 137: 11.26
+	Hs
		497086 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBCE_HUMAN (2499-2885): 5.88e-31: 132: 15.70
+	Hs
		497477 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBCB_HUMAN (2488-2574): 4.4e-31: 126: 28.57
+	Hs
		496396 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CLIP1_HUMAN (2438-2907): 5.59e-21: 103: 16.77
+	Hs
		497731 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CLIP2_HUMAN (2460-2631): 2.61e-19: 98: 28.57
+	Hs
		497209 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR87_HUMAN (2080-2983): 4.86e-16: 87.9: 11.05
+	Hs
		497007 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49
+	Rn
		581930 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DCTN1_RAT (1488-1912): 5.85e-10: 67.6: 19.38
+	Rn
		94152 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DCTN1_RAT (1488-1912): 5.85e-10: 67.6: 19.38
+	Hs
		503287 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		PLEC_HUMAN (1444-2943): 4.71e-31: 137: 11.26
+	Dm
		528062 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		DCTN1_DROME (2493-2828): 9.74e-41: 168: 19.55
+	Hs
		653974 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49
+	Hs
		503286 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		DCTN1_HUMAN (1488-1912): 4.86e-10: 68: 18.49
+	Dm
		1370292 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VTY8_DROME (1787-2706): 1.68e-20: 102: 11.70
+	Dm
		54892 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		A1ZA72_DROME (1303-2936): 5.16e-20: 101: 11.01
+	Dm
		116377 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		M9PI41_DROME (1787-2706): 1.5e-20: 102: 11.70
+	Dm
		973540 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VTY8_DROME (1787-2706): 1.68e-20: 102: 11.70
+	Dm
		1366600 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VH10_DROME (934-2333): 4.78e-12: 74.8: 11.30