HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1117
+	Rn
		581995 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CYTSA_RAT (1-1117): 2.64e-65: 243: 94.37
+	Rn
		94217 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CYTSA_RAT (1-1117): 2.64e-65: 243: 94.37
+	Hs
		496188 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		211474 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (213-1079): 4.97e-34: 144: 10.80
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (213-1079): 4.97e-34: 144: 10.80
+	Hs
		1056862 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CYTSA_HUMAN (1-1117): 1.12e-71: 262: 100.00
+	Hs
		64577 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH7B_HUMAN (384-1031): 1.74e-16: 87.3: 9.35
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (593-1065): 6.18e-14: 79.1: 9.63
+	Hs
		503257 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20