HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1121
+	Hs
		91552 E7EVA0_HUMAN (217-742): 5.43e-26: 117: 24.87		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		203234 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		496652 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		654056 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Rn
		193551 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AFAD_RAT (329-1052): 6.17e-47: 186: 11.79
+	Rn
		94105 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AFAD_RAT (329-1052): 6.17e-47: 186: 11.79
+	Hs
		497461 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		125172 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		654055 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		297818 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		1056986 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		503299 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		1170086 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1056827 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		503297 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		503272 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Hs
		554367 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (699-1115): 4.02e-09: 63.5: 9.20