HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PKN3 (Q6P5Z2)
Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
Gene: PKN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26402096
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 889
+	Hs
		497097 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PKN1_HUMAN (27-883): 0: 888: 51.05
+	Hs
		496245 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCA_HUMAN (379-889): 6.46e-167: 503: 33.65
+	Hs
		408538 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCB_HUMAN (401-887): 1.3e-164: 497: 34.14
+	Hs
		397126 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCG_HUMAN (401-889): 1.25e-156: 477: 33.33
+	Hs
		496408 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT2_HUMAN (431-883): 8.79e-159: 474: 35.15
+	Hs
		496407 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT1_HUMAN (431-883): 2.39e-158: 473: 34.72
+	Hs
		496879 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCE_HUMAN (476-887): 1.37e-149: 460: 37.59
+	Hs
		496317 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6B1_HUMAN (521-888): 8.92e-152: 458: 37.60
+	Rn
		581978 TAU_RAT (1-758): 4.86e-75: 260: 71.47		KPCB_RAT (401-887): 1.51e-163: 494: 33.94
+	Rn
		94201 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		KPCB_RAT (401-887): 1.51e-163: 494: 33.94
+	Mm
		497997 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		KPCG_MOUSE (401-889): 4.51e-156: 476: 33.33
+	Hs
		270366 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KS6A5_HUMAN (453-815): 3.64e-96: 321: 21.94
+	Hs
		152597 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		AKT1_HUMAN (431-883): 2.39e-158: 473: 34.72
+	Hs
		554297 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		KPCD_HUMAN (564-886): 1.29e-90: 303: 48.31