Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.693

The method score is based on:

Property Details
Experiments 36634849, 22565157, 30274285, 21339331, 35063084
Identification Methods proximity labelling technology, affinity chromatography technology, bimolecular fluorescence complementation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005874 - microtubule
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 758
Hs

1 451
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024