HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NEGR1 (Q7Z3B1)
Neuronal growth regulator 1 (IgLON family member 4)
Gene: NEGR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0031175 - neuron projection development GO:0043025 - neuronal cell body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 354
+	Hs
		497905 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO1_HUMAN (1-346): 4.65e-66: 228: 17.31
+	Hs
		497622 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO2_HUMAN (38-351): 3.74e-62: 216: 18.16
+	Hs
		497706 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NTRI_HUMAN (1-133): 1.38e-14: 75.6: 14.18
+	Hs
		496195 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NCAM1_HUMAN (90-312): 5.9e-13: 72: 24.69
+	Hs
		496932 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CNTN1_HUMAN (221-350): 4.29e-12: 69.4: 15.00
+	Hs
		496968 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LSAMP_HUMAN (3-130): 7.61e-12: 67.5: 13.18
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (11-321): 5.63e-09: 60.2: 11.55
+	Mm
		497914 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		CNTN1_MOUSE (221-350): 5.42e-12: 69.1: 15.00