HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CLAP1 (Q7Z460)
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)
Gene: CLASP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005829 - cytosol GO:0008017 - microtubule binding GO:0031116 - positive regulation of microtubule polymerization GO:0070507 - regulation of microtubule cytoskeleton organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1538
+	Hs
		654004 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		CLAP1_HUMAN (1-1522): 0: 1176: 100.00
+	Hs
		297835 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		CLAP1_HUMAN (1-1522): 0: 1176: 100.00
+	Hs
		497372 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GCN1_HUMAN (20-1484): 7.67e-85: 310: 10.97
+	Hs
		496992 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CKAP5_HUMAN (6-1357): 5.44e-31: 135: 12.36
+	Hs
		254542 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CLAP2_HUMAN (7-240): 3.44e-27: 122: 15.97
+	Rn
		582030 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CLAP2_RAT (7-240): 5.07e-27: 122: 15.55
+	Rn
		94256 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CLAP2_RAT (7-240): 5.07e-27: 122: 15.55