HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KI21A (Q7Z4S6)
Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62)
Gene: KIF21A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0030424 - axon GO:0030425 - dendrite
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1674
+	Hs
		496931 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF5A_HUMAN (1-948): 9.19e-130: 434: 20.00
+	Hs
		496422 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KINH_HUMAN (2-963): 2.2e-125: 419: 20.92
+	Hs
		229832 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF5C_HUMAN (2-963): 4.95e-125: 418: 20.58
+	Hs
		496927 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF1A_HUMAN (8-831): 8.29e-118: 412: 23.52
+	Hs
		497871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF3A_HUMAN (9-402): 5.32e-62: 228: 40.65
+	Hs
		166357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KIF3B_HUMAN (9-400): 1.87e-60: 224: 38.75
+	Hs
		253242 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KI21B_HUMAN (1528-1671): 1.92e-14: 81.6: 15.39