HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	25799409
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0008017 - microtubule binding GO:0031122 - cytoplasmic microtubule organization GO:0034452 - dynactin binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 718
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71
+	Hs
		497371 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (466-717): 1.38e-09: 63.8: 10.71
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (308-718): 1.61e-15: 83.1: 10.46
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (308-718): 1.61e-15: 83.1: 10.46
+	Dm
		1370342 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VZT7_DROME (11-706): 3.94e-37: 152: 16.97
+	Ce
		136787 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		MYSP_CAEEL (40-644): 1.29e-23: 108: 10.95