HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SRRM1 (Q8IYB3)
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)
Gene: SRRM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 904
+	Hs
		497126 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MA7D1_HUMAN (112-867): 3.1e-27: 121: 9.91
+	Hs
		152665 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		SRRM1_HUMAN (1-904): 7.55e-73: 259: 100.00
+	Hs
		496871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK2_HUMAN (110-849): 7.77e-11: 68.6: 14.10
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (546-902): 8.17e-11: 68.4: 13.82
+	Hs
		497212 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CRACD_HUMAN (103-899): 3.33e-10: 66.1: 11.04
+	Hs
		497818 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (248-904): 3.57e-16: 85.6: 13.62
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (416-903): 1.56e-10: 67.5: 13.93
+	Rn
		582007 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SYNJ1_RAT (467-904): 4.73e-10: 65.7: 11.49
+	Rn
		94231 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SYNJ1_RAT (467-904): 4.73e-10: 65.7: 11.49
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (487-904): 3.49e-11: 69.6: 12.35
+	Hs
		653987 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		MA7D1_HUMAN (112-867): 3.1e-27: 121: 9.91
+	Dm
		113995 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		Q9VU43_DROME (6-815): 4.26e-31: 133: 22.40
+	Hs
		1056827 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MDC1_HUMAN (204-903): 7.29e-13: 75: 9.61
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (357-903): 1.82e-13: 77.2: 13.36
+	Hs
		1056937 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CHAP1_HUMAN (463-892): 8.67e-10: 64.5: 14.85
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (164-720): 6.29e-11: 68.6: 15.61
+	Hs
		152667 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		KMT2C_HUMAN (390-904): 1.47e-09: 64.6: 11.65
+	Mm
		1207212 NCOA6_MOUSE (23-739): 1.31e-24: 112: 9.76		KMT2C_MOUSE (113-814): 3.96e-09: 63: 10.86
+	Dm
		113984 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		Q9VC60_DROME (504-842): 6.88e-09: 61.7: 17.73