HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ATAD1 (Q8NBU5)
Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (ATPase family AAA domain-containing protein 1) (hATAD1) (Thorase)
Gene: ATAD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36634849, 35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007613 - memory
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 361
+	Hs
		265390 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KTNA1_HUMAN (3-358): 2.78e-107: 324: 31.00
+	Hs
		496752 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS10_HUMAN (8-358): 1.14e-103: 312: 28.65
+	Hs
		496733 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS8_HUMAN (13-359): 2.25e-102: 309: 28.00
+	Hs
		496509 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PRS6B_HUMAN (8-338): 5.06e-99: 301: 26.65
+	Hs
		496648 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TERA_HUMAN (77-356): 3.22e-89: 286: 33.33
+	Mm
		498014 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TERA_MOUSE (77-356): 3.22e-89: 286: 33.33
+	Hs
		497280 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KATL2_HUMAN (85-357): 1.16e-47: 171: 37.59
+	Rn
		545066 MTAP2_RAT (34-758): 4.12e-36: 149: 28.43		KTNA1_RAT (3-358): 1.94e-102: 312: 30.46
+	Dm
		1359411 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9V405_DROME (8-338): 4.02e-101: 306: 26.79
+	Mm
		592777 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		SPAST_MOUSE (88-346): 1.47e-52: 185: 40.39
+	Mm
		1351631 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		SPAST_MOUSE (88-346): 1.47e-52: 185: 40.39