HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CSKI1 (Q8WXD9)
Caskin-1 (CASK-interacting protein 1)
Gene: CASKIN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1431
+	Rn
		582027 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CSKI1_RAT (1-1431): 1.09e-117: 405: 89.69
+	Rn
		94253 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CSKI1_RAT (1-1431): 1.09e-117: 405: 89.69
+	Hs
		60284 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		POTEF_HUMAN (4-542): 1.55e-79: 287: 18.30
+	Hs
		496871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK2_HUMAN (7-274): 2.06e-65: 248: 29.74
+	Rn
		251021 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ANK3_RAT (8-623): 2e-59: 228: 15.94
+	Rn
		94107 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ANK3_RAT (8-623): 2e-59: 228: 15.94
+	Hs
		497375 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANS1A_HUMAN (314-727): 2.67e-17: 90.2: 20.44
+	Hs
		1056981 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TNKS2_HUMAN (5-642): 6.56e-70: 259: 15.36
+	Hs
		310053 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TNKS1_HUMAN (2-614): 1.31e-59: 227: 14.56
+	Hs
		1336188 MAGE1_HUMAN (222-587): 4.83e-09: 61.9: 16.22		KDIS_HUMAN (1-302): 2.04e-72: 269: 23.84
+	Dm
		1182373 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q7KU92_DROME (2-679): 3.8e-68: 257: 16.00
+	Mm
		649211 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		ANS1B_MOUSE (475-599): 4.21e-14: 79.8: 30.08
+	Dm
		1361443 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VAU5_DROME (146-908): 7.68e-29: 128: 10.07
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (338-1087): 3.84e-12: 73.9: 11.51
+	Hs
		1295178 ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94		Q9H4D1_HUMAN (7-112): 4.34e-19: 95.6: 25.47
+	Hs
		883603 ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94		RIPK4_HUMAN (7-112): 6.23e-19: 95.2: 25.47