HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 523
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		497056 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		496310 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (4-522): 4.08e-69: 235: 14.16
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (4-522): 4.08e-69: 235: 14.16
+	Rn
		582003 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NONO_RAT (14-523): 5.41e-66: 222: 53.33
+	Rn
		94227 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NONO_RAT (14-523): 5.41e-66: 222: 53.33
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (4-497): 3.28e-65: 224: 15.24
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		496346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV4_HUMAN (41-156): 2.45e-16: 82.6: 32.79
+	Hs
		496937 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		497082 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		497020 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV3_HUMAN (84-151): 6.6e-13: 72.2: 32.43
+	Hs
		613456 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Mm
		498050 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ELAV4_MOUSE (41-156): 2.45e-16: 82.6: 32.79
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16