HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:1990416 - cellular response to brain-derived neurotrophic factor stimulus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 559
+	Hs
		497812 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WASF3_HUMAN (1-557): 1.12e-43: 164: 45.73
+	Hs
		302246 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SC31A_HUMAN (184-539): 6.75e-29: 124: 12.57
+	Hs
		496924 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Rn
		582007 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SYNJ1_RAT (123-554): 5.15e-35: 142: 12.99
+	Rn
		94231 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SYNJ1_RAT (123-554): 5.15e-35: 142: 12.99
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (41-523): 2.02e-11: 69: 12.53
+	Hs
		496630 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SC24C_HUMAN (164-476): 5.94e-10: 64.3: 12.65
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (289-553): 9.82e-09: 60.5: 14.74
+	Hs
		653964 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		998710 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		554303 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Mm
		222825 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		ACK1_MOUSE (162-530): 2.06e-21: 100: 18.09
+	Hs
		998826 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (188-550): 1.54e-14: 79: 12.95
+	Hs
		152667 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		KMT2C_HUMAN (119-551): 2.63e-12: 72: 13.56
+	Hs
		998981 ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94		EP300_HUMAN (77-554): 1.1e-28: 124: 14.91
+	Mm
		1207212 NCOA6_MOUSE (23-739): 1.31e-24: 112: 9.76		KMT2C_MOUSE (103-508): 7.47e-11: 67.4: 14.12
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (76-548): 8.78e-09: 60.9: 7.99
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (75-540): 2.35e-09: 62.8: 12.82