HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 2671
+	Hs
		497394 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TNPO1_HUMAN (908-1705): 1.2e-50: 198: 13.59
+	Hs
		127171 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		497256 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		496391 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		2AAA_HUMAN (959-1405): 1.51e-19: 97.8: 12.22
+	Hs
		496992 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33
+	Rn
		581987 TAU_RAT (1-758): 4.86e-75: 260: 71.47		CAND1_RAT (1460-2587): 1.93e-22: 108: 13.61
+	Rn
		94209 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		CAND1_RAT (1460-2587): 1.93e-22: 108: 13.61
+	Hs
		497173 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Mm
		498063 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		CAND1_MOUSE (1460-2587): 3.03e-22: 107: 13.61
+	Mm
		498064 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		2AAA_MOUSE (959-1405): 1.24e-19: 97.8: 12.22
+	Dm
		1370249 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VPR5_DROME (1207-2087): 6.94e-61: 233: 13.54
+	Dm
		1369715 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CAND1_DROME (1333-2593): 1.83e-54: 212: 13.27
+	Hs
		127176 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Dm
		734228 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		2AAA_DROME (959-1395): 6.8e-14: 79.7: 11.39