HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DDX17 (Q92841)
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72)
Gene: DDX17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 729
+	Mm
		498030 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DDX17_MOUSE (106-717): 0: 580: 98.86
+	Hs
		496251 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX5_HUMAN (82-715): 6.38e-164: 487: 66.41
+	Hs
		497260 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX42_HUMAN (17-686): 2.46e-144: 447: 31.87
+	Hs
		133854 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX3X_HUMAN (22-581): 1.42e-142: 434: 37.06
+	Hs
		497225 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DDX46_HUMAN (28-711): 3.57e-138: 434: 31.48
+	Mm
		498084 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q8BTS0_MOUSE (82-715): 4.05e-164: 488: 65.99
+	Mm
		498056 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DDX3Y_MOUSE (19-579): 1.12e-136: 419: 35.20
+	Dm
		1370335 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VXW2_DROME (130-551): 2.61e-107: 355: 44.71