HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: EFHD2 (Q96C19)
EF-hand domain-containing protein D2 (Swiprosin-1)
Gene: EFHD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045121 - membrane raft
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 240
+	Mm
		498087 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q8C845_MOUSE (1-240): 1.66e-67: 210: 93.36
+	Hs
		496267 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ML12A_HUMAN (72-179): 3.78e-34: 122: 29.63
+	Hs
		580649 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ML12A_HUMAN (72-179): 3.78e-34: 122: 29.63
+	Dm
		773044 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		SQH_DROME (67-179): 4.46e-29: 109: 24.78
+	Dm
		906720 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CALM_DROME (47-160): 8.02e-22: 89.7: 23.02
+	Bt
		664290 TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00		CALM_BOVIN (47-160): 9.7e-22: 89.3: 22.22
+	At
		886573 Q8LPR4_ARATH (228-586): 1e-09: 64.2: 19.60		CALM7_ARATH (47-160): 1.29e-20: 86.6: 23.02
+	At
		99092 F4K946_ARATH (228-586): 9.93e-10: 64.2: 19.60		CALM7_ARATH (47-160): 1.29e-20: 86.6: 23.02
+	At
		976645 Q8LPR4_ARATH (228-586): 1e-09: 64.2: 19.60		CALM6_ARATH (47-160): 3.78e-20: 85.1: 22.22
+	At
		99093 F4K946_ARATH (228-586): 9.93e-10: 64.2: 19.60		CALM6_ARATH (47-160): 3.78e-20: 85.1: 22.22
+	At
		626359 Q8LPR4_ARATH (228-586): 1e-09: 64.2: 19.60		CML12_ARATH (88-159): 1.37e-15: 76.5: 31.94