HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MSI2H (Q96DH6)
RNA-binding protein Musashi homolog 2 (Musashi-2)
Gene: MSI2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	30367664, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 328
+	Hs
		496607 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROA3_HUMAN (15-193): 6.74e-76: 239: 41.99
+	Hs
		453100 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROA1_HUMAN (12-193): 3.31e-74: 234: 41.18
+	Hs
		201653 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MSI1H_HUMAN (1-328): 9.87e-73: 230: 66.94
+	Rn
		582022 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ROA3_RAT (15-193): 6.93e-76: 239: 41.99
+	Rn
		94248 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ROA3_RAT (15-193): 6.93e-76: 239: 41.99
+	Hs
		496995 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRPD_HUMAN (6-289): 3.47e-55: 185: 35.21
+	Hs
		497496 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROAA_HUMAN (2-289): 1.19e-53: 180: 36.21
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (12-264): 4.39e-43: 158: 17.26
+	Hs
		496306 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROA2_HUMAN (96-206): 4.25e-26: 108: 33.33
+	Hs
		161944 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HNRDL_HUMAN (72-204): 1e-19: 91: 28.57
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48
+	Rn
		64991 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ROA2_RAT (96-206): 4.99e-26: 107: 33.33
+	Rn
		64993 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ROA2_RAT (96-206): 4.99e-26: 107: 33.33
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (100-190): 1.6e-15: 79.3: 18.48
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (100-190): 1.6e-15: 79.3: 18.48
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (100-190): 7.66e-16: 80: 19.57
+	Hs
		654044 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		ROAA_HUMAN (2-289): 1.19e-53: 180: 36.21
+	Hs
		1056955 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ROAA_HUMAN (2-289): 1.19e-53: 180: 36.21
+	Dm
		995786 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		SQD_DROME (3-192): 2.1e-53: 180: 37.90
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (100-190): 1.7e-15: 79.3: 18.48