HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: H2A1H (Q96KK5)
Histone H2A type 1-H (H2A-clustered histone 12) (Histone H2A/s)
Gene: H2AC12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32812023
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 128
+	Hs
		497504 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H2A1J_HUMAN (1-128): 2.71e-67: 200: 99.22
+	Hs
		391521 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H2A1B_HUMAN (1-128): 1.07e-66: 199: 98.44
+	Hs
		497112 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H2A2C_HUMAN (1-124): 8.56e-65: 194: 98.39
+	Hs
		496230 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H2AX_HUMAN (1-124): 2.04e-63: 191: 94.36
+	Rn
		69274 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		H2AJ_RAT (1-124): 1.2e-64: 194: 96.77
+	Rn
		69275 TAU_RAT (1-758): 4.86e-75: 260: 71.47		H2AJ_RAT (1-124): 1.2e-64: 194: 96.77
+	Hs
		654009 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		H2A2B_HUMAN (1-128): 1.07e-65: 196: 95.31
+	Hs
		152575 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		H2A1B_HUMAN (1-128): 1.07e-66: 199: 98.44
+	Hs
		555463 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		H2AX_HUMAN (1-124): 2.04e-63: 191: 94.36
+	Hs
		554260 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		H2AX_HUMAN (1-124): 2.04e-63: 191: 94.36
+	Hs
		1273164 PRG4_HUMAN (4-604): 5.21e-20: 97.8: 8.93		H2A1H_HUMAN (1-128): 2.32e-67: 200: 100.00
+	Hs
		391802 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		H2A1B_HUMAN (1-128): 1.07e-66: 199: 98.44