HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PASK (Q96RG2)
PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)
Gene: PASK

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21418524
Identification Methods	peptide array
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035091 - phosphatidylinositol binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1323
+	Hs
		496879 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCE_HUMAN (777-1318): 3.16e-125: 407: 18.91
+	Hs
		496408 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT2_HUMAN (897-1310): 5.61e-125: 397: 20.75
+	Hs
		496492 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KPCI_HUMAN (843-1321): 6.68e-122: 393: 19.37
+	Hs
		496407 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AKT1_HUMAN (897-1313): 2.45e-121: 387: 19.95
+	Hs
		496358 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MARK3_HUMAN (990-1272): 4.07e-108: 360: 33.22
+	Hs
		152597 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		AKT1_HUMAN (897-1313): 2.45e-121: 387: 19.95
+	Hs
		503266 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		MARK3_HUMAN (990-1272): 4.07e-108: 360: 33.22
+	Hs
		497224 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MARK2_HUMAN (989-1251): 2.4e-37: 154: 36.43
+	Hs
		497452 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MARK4_HUMAN (988-1272): 6.86e-36: 149: 34.13
+	Hs
		497338 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		BRSK1_HUMAN (993-1250): 9.9e-36: 148: 34.47
+	Hs
		654032 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		MARK4_HUMAN (988-1272): 6.86e-36: 149: 34.13
+	Hs
		503298 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		MARK4_HUMAN (988-1272): 6.86e-36: 149: 34.13