HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NEB2 (Q96SB3)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: PPP1R9B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0030426 - growth cone GO:0031175 - neuron projection development and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 817
+	Mm
		592771 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		497254 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Mm
		581225 NFH_MOUSE (284-730): 4.84e-16: 84.7: 14.99		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		88462 D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Mm
		1164093 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		NEB2_MOUSE (1-817): 9.52e-117: 375: 96.21
+	Hs
		496652 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Hs
		496940 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DLG1_HUMAN (435-691): 6e-19: 94.1: 15.04
+	Rn
		193551 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AFAD_RAT (413-639): 1.35e-27: 122: 27.00
+	Rn
		94105 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AFAD_RAT (413-639): 1.35e-27: 122: 27.00
+	Hs
		497466 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MAGI1_HUMAN (462-688): 1.9e-10: 66.9: 10.48
+	Hs
		497866 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GRIP1_HUMAN (165-625): 4.18e-10: 65.8: 11.57
+	Hs
		654006 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		654037 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		ERBIN_HUMAN (11-583): 1.56e-42: 170: 13.02
+	Hs
		1200041 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		RIMS1_HUMAN (126-637): 9e-45: 177: 17.41
+	Hs
		297818 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		AFAD_HUMAN (411-642): 8.91e-29: 126: 27.69
+	Mm
		581224 NFH_MOUSE (284-730): 4.84e-16: 84.7: 14.99		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Mm
		88458 D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Mm
		1143433 SYNJ1_MOUSE (129-637): 3.11e-11: 69.3: 11.20		DLG4_MOUSE (438-714): 8.12e-28: 122: 16.38
+	Ce
		103468 TTN1_CAEEL (4-632): 3.28e-10: 66.1: 11.61		DLG1_CAEEL (349-585): 3.47e-20: 98.1: 17.30