HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: MA7D2 (Q96T17)
MAP7 domain-containing protein 2
Gene: MAP7D2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0015630 - microtubule cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 732
+	Hs
		497126 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MA7D1_HUMAN (4-649): 2.82e-47: 182: 18.31
+	Hs
		497011 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MAP7_HUMAN (8-585): 4.61e-26: 116: 27.32
+	Hs
		496652 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AFAD_HUMAN (6-492): 1.38e-25: 115: 12.05
+	Hs
		496432 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MERL_HUMAN (423-657): 3.92e-20: 97.1: 23.65
+	Rn
		193551 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AFAD_RAT (6-492): 7.06e-27: 120: 11.86
+	Rn
		94105 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AFAD_RAT (6-492): 7.06e-27: 120: 11.86
+	Hs
		497209 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR87_HUMAN (38-668): 1.17e-09: 64.2: 13.15
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (66-664): 1.16e-21: 102: 11.42
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (93-641): 5.91e-09: 61.9: 9.75
+	Hs
		497051 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PLEC_HUMAN (34-607): 6.74e-09: 61.6: 15.03
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (91-664): 2.74e-20: 98.5: 11.53
+	Hs
		653987 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		MA7D1_HUMAN (4-649): 2.82e-47: 182: 18.31
+	Hs
		148818 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CTRO_HUMAN (43-611): 1.37e-32: 138: 11.64
+	Hs
		149481 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		CTRO_HUMAN (43-611): 1.37e-32: 138: 11.64
+	Dm
		54348 A1Z9J3_DROME (14-746): 5.58e-33: 139: 11.47		Q9W053_DROME (403-606): 2.06e-15: 82.8: 19.05
+	Mm
		592772 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		TAOK2_MOUSE (200-674): 1.21e-17: 90: 11.36
+	Hs
		297818 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		AFAD_HUMAN (6-492): 1.38e-25: 115: 12.05
+	Mm
		649210 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		TAOK2_MOUSE (200-674): 1.21e-17: 90: 11.36
+	Hs
		503287 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		PLEC_HUMAN (34-607): 6.74e-09: 61.6: 15.03
+	Dm
		54892 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		A1ZA72_DROME (7-668): 5.49e-21: 101: 10.79