HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: S10AD (Q99584)
Protein S100-A13 (S100 calcium-binding protein A13)
Gene: S100A13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 98
+	Hs
		497264 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HORN_HUMAN (6-89): 2.99e-30: 114: 29.89
+	Hs
		496312 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A1_HUMAN (7-91): 2.29e-30: 104: 37.50
+	Hs
		496690 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AA_HUMAN (6-98): 1.32e-29: 102: 26.04
+	Hs
		416341 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A9_HUMAN (5-93): 7.13e-29: 101: 32.26
+	Hs
		497147 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FILA2_HUMAN (6-89): 3.52e-25: 99.5: 33.33
+	Hs
		380723 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S100B_HUMAN (6-91): 3.01e-27: 96.8: 26.97
+	Hs
		396671 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A8_HUMAN (6-98): 4.03e-25: 91.4: 23.66
+	Hs
		497435 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10AG_HUMAN (3-97): 7.39e-24: 88.7: 29.29
+	Hs
		416558 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S10A6_HUMAN (8-91): 2.55e-23: 86.8: 31.77
+	Hs
		496287 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		FILA_HUMAN (6-89): 5.56e-19: 81.8: 25.29
+	Hs
		152595 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		S10A2_HUMAN (7-91): 3.32e-26: 94.5: 32.96
+	Bt
		361268 TAU_BOVIN (1-291): 3.66e-12: 71.3: 40.00		S100B_BOVIN (6-91): 9.64e-28: 98.4: 26.97