HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DPYL5 (Q9BPU6)
Dihydropyrimidinase-related protein 5 (DRP-5) (CRMP3-associated molecule) (CRAM) (Collapsin response mediator protein 5) (CRMP-5) (UNC33-like phosphoprotein 6) (ULIP-6)
Gene: DPYSL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030425 - dendrite GO:0043025 - neuronal cell body
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 564
+	Hs
		497005 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL1_HUMAN (6-561): 0: 729: 50.81
+	Hs
		497102 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL2_HUMAN (6-561): 0: 726: 51.71
+	Hs
		497006 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL3_HUMAN (6-561): 0: 721: 51.08
+	Hs
		147310 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DPYL4_HUMAN (6-561): 0: 715: 49.46
+	Rn
		581948 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DPYL2_RAT (6-561): 0: 725: 52.24
+	Rn
		94172 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DPYL2_RAT (6-561): 0: 725: 52.24
+	Rn
		582008 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DPYL1_RAT (6-561): 0: 722: 49.91
+	Rn
		94232 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DPYL1_RAT (6-561): 0: 722: 49.91
+	Mm
		498057 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		DPYL3_MOUSE (6-561): 0: 719: 51.26