HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton and 1 others more... GO:0045121 - membrane raft
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 449
+	Hs
		496818 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		496817 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		497220 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		427983 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		497683 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA8_HUMAN (1-439): 0: 698: 90.66
+	Hs
		496819 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		497534 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Rn
		582020 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TBA1B_RAT (1-439): 0: 717: 99.09
+	Rn
		94246 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TBA1B_RAT (1-439): 0: 717: 99.09
+	Mm
		399082 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBA1B_MOUSE (1-439): 0: 717: 99.09
+	Mm
		498002 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBA1A_MOUSE (1-439): 0: 715: 99.09
+	Mm
		498012 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBB5_MOUSE (1-439): 0: 699: 41.00
+	Hs
		653957 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		503294 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Mm
		649204 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		TBA1A_MOUSE (1-439): 0: 715: 99.09
+	Hs
		92120 NACAM_HUMAN (203-750): 1.03e-12: 74.3: 9.75		TBA1A_HUMAN (1-439): 0: 715: 99.09