HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TBB6 (Q9BUF5)
Tubulin beta-6 chain (Tubulin beta class V)
Gene: TUBB6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 446
+	Hs
		496973 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB3_HUMAN (1-446): 0: 727: 92.38
+	Hs
		427983 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB5_HUMAN (1-429): 0: 719: 92.54
+	Hs
		496819 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB4B_HUMAN (1-427): 0: 717: 92.74
+	Hs
		497534 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB2B_HUMAN (1-430): 0: 717: 92.79
+	Hs
		496991 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB2A_HUMAN (1-430): 0: 714: 92.56
+	Hs
		381106 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB4A_HUMAN (1-427): 0: 713: 93.44
+	Hs
		497129 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB8_HUMAN (1-427): 0: 703: 87.12
+	Rn
		94224 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TBB3_RAT (1-446): 0: 725: 92.15
+	Rn
		581999 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TBB2B_RAT (1-430): 0: 717: 92.79
+	Rn
		94221 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TBB2B_RAT (1-430): 0: 717: 92.79
+	Mm
		498142 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBB3_MOUSE (1-446): 0: 725: 92.15
+	Mm
		498012 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBB5_MOUSE (1-429): 0: 719: 92.54
+	Mm
		498126 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBB2B_MOUSE (1-430): 0: 717: 92.79
+	Mm
		498110 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBB6_MOUSE (1-431): 0: 712: 97.91
+	Hs
		503283 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		TBB3_HUMAN (1-446): 0: 727: 92.38