HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 310
+	Hs
		497034 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HECAM_HUMAN (2-290): 3.83e-42: 151: 22.64
+	Hs
		496825 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		497905 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		497706 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NTRI_HUMAN (11-241): 2.72e-30: 118: 21.28
+	Hs
		496195 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NCAM1_HUMAN (18-306): 7.35e-25: 106: 12.91
+	Hs
		497622 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO2_HUMAN (134-310): 1.67e-19: 91.1: 15.71
+	Hs
		497387 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69
+	Hs
		178058 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NCAM2_HUMAN (31-226): 4.65e-14: 74.4: 20.20
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (44-243): 7.16e-09: 59.1: 12.21
+	Hs
		297826 K0754_HUMAN (5-450): 2.95e-22: 105: 11.86		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		1056924 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ESAM_HUMAN (15-238): 5.34e-29: 116: 22.49