HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AP1M1 (Q9BXS5)
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)
Gene: AP1M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 423
+	Hs
		497422 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Rn
		581982 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AP2M1_RAT (3-421): 3.27e-155: 447: 38.85
+	Rn
		94205 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AP2M1_RAT (3-421): 3.27e-155: 447: 38.85
+	Mm
		498008 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		AP2M1_MOUSE (3-421): 3.27e-155: 447: 38.85
+	Hs
		497844 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP3M1_HUMAN (3-422): 5.32e-127: 375: 26.73
+	Hs
		496626 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP3M2_HUMAN (3-422): 2.67e-123: 365: 25.81
+	Hs
		654028 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Dm
		248311 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		O62530_DROME (3-421): 4.47e-152: 439: 39.36
+	Hs
		203244 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		AP2M1_HUMAN (3-421): 3.27e-155: 447: 38.85
+	Hs
		496542 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72