HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CADM1 (Q9BY67)
Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)
Gene: CADM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0043005 - neuron projection
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 442
+	Hs
		497294 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM2_HUMAN (25-442): 1.95e-76: 246: 42.26
+	Hs
		497288 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM3_HUMAN (15-442): 1.01e-72: 236: 36.57
+	Hs
		497325 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CADM4_HUMAN (45-442): 2.31e-72: 234: 34.93
+	Hs
		497055 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NECT1_HUMAN (28-410): 5.14e-64: 216: 23.42
+	Hs
		497238 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NEGR1_HUMAN (1-349): 5.04e-64: 212: 20.06
+	Hs
		497706 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NTRI_HUMAN (29-328): 8.51e-61: 203: 23.47
+	Hs
		497905 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO1_HUMAN (12-420): 4.27e-54: 196: 14.58
+	Hs
		496932 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CNTN1_HUMAN (107-442): 3.17e-37: 146: 9.70
+	Hs
		178058 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NCAM2_HUMAN (52-361): 4.46e-35: 140: 20.32
+	Hs
		497622 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ROBO2_HUMAN (6-364): 6.1e-15: 79.5: 12.94
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (135-439): 9.8e-09: 59.9: 14.38