HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: ACTBM (Q9BYX7)
Putative beta-actin-like protein 3 (Kappa-actin) (POTE ankyrin domain family member K)
Gene: POTEKP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030424 - axon
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 375
+	Hs
		60284 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		POTEF_HUMAN (1-375): 0: 746: 94.13
+	Hs
		496683 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTB_HUMAN (1-375): 0: 599: 91.47
+	Hs
		496806 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTG_HUMAN (1-375): 0: 599: 90.93
+	Hs
		496759 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTA_HUMAN (2-375): 0: 589: 86.90
+	Hs
		496813 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTC_HUMAN (2-375): 0: 589: 87.17
+	Hs
		496816 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACTS_HUMAN (2-375): 0: 589: 86.63
+	Mm
		498001 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ACTC_MOUSE (2-375): 0: 589: 87.17
+	Hs
		503276 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		ACTB_HUMAN (1-375): 0: 599: 91.47
+	Hs
		932156 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		ACTC_HUMAN (2-375): 0: 589: 87.17
+	Ce
		501479 Q95QG4_CAEEL (411-693): 9.33e-25: 110: 29.33		ACT4_CAEEL (2-375): 0: 596: 89.31
+	Ce
		109402 H2KY94_CAEEL (465-688): 3.39e-25: 107: 33.48		ACT4_CAEEL (2-375): 0: 596: 89.31
+	Hs
		554290 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		ACTA_HUMAN (2-375): 0: 589: 86.90
+	Hs
		891853 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		ACTB_HUMAN (1-375): 0: 599: 91.47
+	Hs
		929905 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		ACTG_HUMAN (1-375): 0: 599: 90.93
+	Ce
		137705 O02592_CAEEL (353-709): 5.66e-13: 73.8: 21.29		ACT4_CAEEL (2-375): 0: 596: 89.31
+	Hs
		932219 SRCAP_HUMAN (2-474): 1.09e-12: 74.3: 9.83		ACTC_HUMAN (2-375): 0: 589: 87.17
+	Dm
		501445 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		ACT5_DROME (2-375): 0: 593: 88.24
+	Hs
		203220 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		ACTC_HUMAN (2-375): 0: 589: 87.17