HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: UBE2O (Q9C0C9)
(E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)
Gene: UBE2O

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1292
+	Hs
		496768 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D2_HUMAN (953-1106): 1.71e-62: 211: 22.29
+	Hs
		496697 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UB2D3_HUMAN (953-1106): 2.98e-61: 207: 22.93
+	Hs
		497630 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBE2T_HUMAN (956-1135): 5.53e-55: 191: 26.52
+	Hs
		496700 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBE2N_HUMAN (956-1103): 1.44e-45: 163: 22.52
+	Dm
		973539 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9VQ00_DROME (951-1106): 4.89e-58: 199: 20.13