HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GHC1 (Q9H936)
Mitochondrial glutamate carrier 1 (GC-1) (Glutamate/H(+) symporter 1) (Solute carrier family 25 member 22)
Gene: SLC25A22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 323
+	Mm
		498134 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GHC1_MOUSE (1-323): 1.86e-100: 299: 95.67
+	Hs
		496183 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT1_HUMAN (97-322): 2.72e-38: 139: 19.48
+	Hs
		397240 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT2_HUMAN (101-322): 5.12e-38: 138: 18.50
+	Hs
		1056992 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		GHC1_HUMAN (1-323): 5.73e-99: 296: 100.00
+	Hs
		496620 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TXTP_HUMAN (5-306): 1.85e-24: 102: 27.10
+	Rn
		581991 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT1_RAT (97-322): 6.84e-39: 140: 19.91
+	Rn
		94213 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT1_RAT (97-322): 6.84e-39: 140: 19.91
+	Rn
		581994 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ADT2_RAT (101-322): 3.58e-38: 138: 18.50
+	Rn
		94216 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ADT2_RAT (101-322): 3.58e-38: 138: 18.50
+	Hs
		497760 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2513_HUMAN (229-323): 2.62e-21: 96.5: 32.65
+	Hs
		274476 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		S2512_HUMAN (2-106): 1.04e-20: 94.6: 25.47
+	Mm
		497947 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT1_MOUSE (97-322): 6.03e-39: 141: 19.91
+	Mm
		497951 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		ADT2_MOUSE (101-322): 2.78e-38: 139: 18.50
+	Hs
		496184 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ADT3_HUMAN (224-322): 3.75e-13: 70.7: 25.49
+	Mm
		498076 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		S2512_MOUSE (2-106): 1.85e-20: 93.8: 25.47