HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031175 - neuron projection development
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 208
+	Hs
		496282 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		496592 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		497392 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB8B_HUMAN (10-207): 6.35e-89: 261: 38.31
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Hs
		496283 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		497091 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11B_HUMAN (7-208): 5.29e-82: 244: 28.91
+	Mm
		497936 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5C_MOUSE (3-207): 2.45e-89: 263: 40.98
+	Mm
		498121 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5A_MOUSE (3-207): 1.93e-89: 263: 41.26
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (1-207): 7.26e-89: 261: 34.30
+	Mm
		497966 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB6B_MOUSE (1-208): 4.46e-87: 257: 100.00
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (7-206): 2.65e-87: 257: 36.50
+	Hs
		496695 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5B_HUMAN (13-178): 5.66e-49: 160: 45.78
+	Hs
		496694 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		108975 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H0YNE9_HUMAN (14-171): 5.4e-45: 149: 45.57
+	Hs
		592112 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78