HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: KLC4 (Q9NSK0)
Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)
Gene: KLC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005874 - microtubule
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 619
+	Hs
		497576 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KLC2_HUMAN (11-619): 1.04e-108: 342: 68.70
+	Hs
		496914 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		KLC1_HUMAN (1-544): 7.47e-98: 312: 68.99
+	Rn
		70311 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		B2GV74_RAT (1-619): 2.4e-105: 333: 68.88
+	Rn
		94162 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		KLC1_RAT (1-544): 7.21e-95: 304: 68.62
+	Hs
		174574 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		OGT1_HUMAN (93-614): 2.89e-49: 186: 15.52
+	Hs
		174891 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		OGT1_HUMAN (93-614): 2.89e-49: 186: 15.52
+	Hs
		175053 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		OGT1_HUMAN (93-614): 2.89e-49: 186: 15.52
+	Hs
		672833 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CDC27_HUMAN (19-369): 1.69e-20: 98.2: 13.20
+	Mm
		649209 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		CLU_MOUSE (130-333): 1.79e-18: 92: 19.61
+	Dm
		1370278 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VSK6_DROME (143-615): 3.52e-23: 107: 10.36