HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TBA8 (Q9NY65)
Tubulin alpha-8 chain (EC 3.6.5.-) (Alpha-tubulin 8) (Tubulin alpha chain-like 2) [Cleaved into: Dephenylalaninated tubulin alpha-8 chain]
Gene: TUBA8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32812023, 26269332
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0015630 - microtubule cytoskeleton
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 449
+	Hs
		497515 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA1C_HUMAN (1-449): 0: 717: 89.76
+	Hs
		496818 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA4A_HUMAN (1-448): 0: 710: 89.96
+	Hs
		496817 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		497220 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Hs
		427983 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB5_HUMAN (1-439): 0: 694: 39.41
+	Hs
		496819 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBB4B_HUMAN (1-437): 0: 691: 39.13
+	Rn
		582020 TAU_RAT (1-758): 4.86e-75: 260: 71.47		TBA1B_RAT (1-439): 0: 706: 90.89
+	Rn
		94246 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		TBA1B_RAT (1-439): 0: 706: 90.89
+	Mm
		399082 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBA1B_MOUSE (1-439): 0: 706: 90.89
+	Mm
		498002 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBA1A_MOUSE (1-439): 0: 704: 90.89
+	Mm
		498012 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		TBB5_MOUSE (1-439): 0: 694: 39.41
+	Hs
		653957 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		TBA1B_HUMAN (1-439): 0: 706: 90.89
+	Hs
		503294 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		TBA1A_HUMAN (1-439): 0: 704: 90.89
+	Mm
		649204 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		TBA1A_MOUSE (1-439): 0: 704: 90.89
+	Hs
		92120 NACAM_HUMAN (203-750): 1.03e-12: 74.3: 9.75		TBA1A_HUMAN (1-439): 0: 704: 90.89