HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 693
+	Hs
		497300 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		496891 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		496597 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55
+	Rn
		582007 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SYNJ1_RAT (252-668): 1.66e-10: 66.7: 9.72
+	Rn
		94231 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SYNJ1_RAT (252-668): 1.66e-10: 66.7: 9.72
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (234-663): 1.16e-10: 67.5: 10.99
+	Hs
		1056876 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MICA3_HUMAN (139-605): 2.54e-25: 114: 11.18
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Hs
		152667 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		KMT2C_HUMAN (103-538): 1.38e-09: 63.9: 14.25
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (55-589): 2.76e-10: 66.3: 11.45
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (72-652): 3.01e-19: 95.2: 10.64
+	Dm
		375663 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		RPB1_DROME (131-425): 5.47e-11: 68.5: 15.27