HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CLIP2 (Q9UDT6)
CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2) (Williams-Beuren syndrome chromosomal region 3 protein) (Williams-Beuren syndrome chromosomal region 4 protein)
Gene: CLIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008017 - microtubule binding GO:0031122 - cytoplasmic microtubule organization
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1046
+	Hs
		496438 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH9_HUMAN (649-1045): 2.84e-15: 83.4: 10.47
+	Hs
		497769 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH2_HUMAN (693-1046): 2.29e-14: 80.3: 11.45
+	Hs
		496228 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DESP_HUMAN (349-885): 6.52e-14: 79: 13.82
+	Hs
		496439 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		MYH10_HUMAN (699-1045): 2.84e-13: 76.8: 12.00
+	Hs
		496396 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CLIP1_HUMAN (515-1046): 6.42e-13: 75.7: 9.01
+	Hs
		497170 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CE350_HUMAN (74-149): 1.84e-11: 70.9: 48.68
+	Hs
		497477 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TBCB_HUMAN (93-146): 1.3e-11: 67.8: 55.56
+	Hs
		497007 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		DCTN1_HUMAN (636-1015): 1.69e-10: 67.5: 17.69
+	Rn
		582036 TAU_RAT (1-758): 4.86e-75: 260: 71.47		MYH10_RAT (691-1046): 2.78e-13: 76.9: 10.67
+	Rn
		94262 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		MYH10_RAT (691-1046): 2.78e-13: 76.9: 10.67
+	Rn
		581930 TAU_RAT (1-758): 4.86e-75: 260: 71.47		DCTN1_RAT (658-972): 1.59e-09: 64.4: 15.95
+	Rn
		94152 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		DCTN1_RAT (658-972): 1.59e-09: 64.4: 15.95
+	Hs
		653974 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		DCTN1_HUMAN (636-1015): 1.69e-10: 67.5: 17.69
+	Hs
		503286 MTAP2_HUMAN (16-758): 2.28e-30: 131: 23.55		DCTN1_HUMAN (636-1015): 1.69e-10: 67.5: 17.69
+	Dm
		528062 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		DCTN1_DROME (216-629): 4.77e-09: 62.8: 25.90