HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CNTP2 (Q9UHC6)
Contactin-associated protein-like 2 (Cell recognition molecule Caspr2)
Gene: CNTNAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019899 - enzyme binding GO:0030424 - axon GO:0030425 - dendrite GO:0030673 - axolemma GO:0031175 - neuron projection development and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1331
+	Mm
		592775 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		CNTP2_MOUSE (1-1331): 0: 1086: 93.84
+	Mm
		649220 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		CNTP2_MOUSE (1-1331): 0: 1086: 93.84
+	Hs
		497717 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NRX2A_HUMAN (383-596): 2.24e-21: 103: 15.91
+	Hs
		497778 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NRX1A_HUMAN (367-593): 9.46e-21: 101: 19.67
+	Hs
		496332 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LAMA1_HUMAN (538-797): 4.77e-12: 73.4: 15.64
+	Hs
		265154 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		USH2A_HUMAN (810-975): 4.42e-11: 70.2: 25.28
+	Mm
		592776 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		NRX1A_MOUSE (383-593): 3.32e-20: 100: 19.91
+	Mm
		649221 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		NRX1A_MOUSE (383-593): 3.32e-20: 100: 19.91