HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: UBQL2 (Q9UHD9)
Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2)
Gene: UBQLN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35063084, 26269332
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 624
+	Hs
		497794 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBQL1_HUMAN (1-624): 8.68e-147: 439: 71.52
+	Hs
		497650 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		UBQL4_HUMAN (22-624): 2.17e-124: 382: 54.55
+	Hs
		1057015 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		UBQL2_HUMAN (1-624): 1.19e-153: 458: 100.00
+	Hs
		496518 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		BAG6_HUMAN (21-580): 4.44e-53: 198: 15.23
+	Hs
		496787 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RL40_HUMAN (33-112): 7.49e-34: 127: 30.86
+	Hs
		496786 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RS27A_HUMAN (33-119): 4.49e-24: 100: 27.27
+	Hs
		99716 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		F5H265_HUMAN (33-103): 1.18e-12: 67.7: 33.33
+	Mm
		497988 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RS27A_MOUSE (33-119): 5.82e-13: 68.8: 27.27