HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 559
+	Rn
		582044 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PUF60_RAT (1-559): 4.79e-101: 318: 97.52
+	Hs
		497019 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		496937 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		496346 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ELAV4_HUMAN (16-210): 6.97e-20: 93.7: 16.92
+	Hs
		311335 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CELF2_HUMAN (116-203): 3.74e-17: 86.5: 31.82
+	Hs
		496957 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		496179 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1054314 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Rn
		582032 TAU_RAT (1-758): 4.86e-75: 260: 71.47		PABP1_RAT (457-550): 3.88e-10: 64.5: 10.64
+	Rn
		94258 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		PABP1_RAT (457-550): 3.88e-10: 64.5: 10.64
+	Mm
		498054 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q62029_MOUSE (31-135): 6.04e-10: 63.8: 5.71
+	Hs
		516595 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64