HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: RB22A (Q9UL26)
Ras-related protein Rab-22A (Rab-22)
Gene: RAB22A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 194
+	Hs
		496592 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5C_HUMAN (5-194): 8.52e-88: 258: 47.94
+	Hs
		496282 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5A_HUMAN (5-194): 4.31e-85: 251: 47.94
+	Hs
		496695 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB5B_HUMAN (5-194): 9.06e-85: 251: 47.94
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (6-194): 2.29e-83: 246: 36.60
+	Hs
		497581 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1B_HUMAN (6-194): 5.61e-83: 245: 36.27
+	Hs
		496754 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RB11A_HUMAN (1-194): 1.99e-79: 237: 35.21
+	Hs
		496696 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB10_HUMAN (1-194): 1.97e-79: 236: 34.00
+	Mm
		497936 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5C_MOUSE (5-194): 1.14e-87: 258: 47.94
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (6-194): 2.29e-83: 246: 36.60
+	Mm
		498132 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1B_MOUSE (6-194): 1.17e-82: 245: 36.27
+	Mm
		498121 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB5A_MOUSE (5-194): 6.92e-81: 241: 47.94
+	Mm
		497961 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB10_MOUSE (1-194): 1.97e-79: 236: 34.00
+	Hs
		592112 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		RAB5A_HUMAN (5-194): 4.31e-85: 251: 47.94
+	Mm
		649199 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		RB22A_MOUSE (1-194): 4.86e-81: 240: 97.42