HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NRX1A (Q9ULB1)
Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha)
Gene: NRXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007416 - synapse assembly GO:0043025 - neuronal cell body
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1477
+	Mm
		592776 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		NRX1A_MOUSE (24-1477): 0: 1180: 96.78
+	Mm
		649221 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		NRX1A_MOUSE (24-1477): 0: 1180: 96.78
+	Hs
		497717 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NRX2A_HUMAN (2-135): 8.2e-14: 79.2: 22.76
+	Hs
		497744 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CNTP2_HUMAN (54-212): 1.73e-11: 71.5: 17.47
+	Hs
		496332 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LAMA1_HUMAN (18-189): 5.23e-10: 66.9: 16.00
+	Mm
		592775 MTAP2_MOUSE (26-758): 1.71e-30: 131: 23.89		CNTP2_MOUSE (31-212): 4.5e-13: 76.5: 17.37
+	Mm
		649220 MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63		CNTP2_MOUSE (31-212): 4.5e-13: 76.5: 17.37