HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: NDRG2 (Q9UN36)
Protein NDRG2 (N-myc downstream-regulated gene 2 protein) (Protein Syld709613)
Gene: NDRG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35063084, 26402096
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030426 - growth cone
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 371
+	Rn
		582026 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NDRG2_RAT (1-371): 0: 568: 95.96
+	Rn
		94252 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		NDRG2_RAT (1-371): 0: 568: 95.96
+	Hs
		497784 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		NDRG4_HUMAN (40-371): 2.55e-169: 478: 62.46
+	Dm
		1370241 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q9VNH7_DROME (38-351): 1.83e-123: 362: 29.63