HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CSN3 (Q9UNS2)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)
Gene: COPS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 423
+	Hs
		198531 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSMD3_HUMAN (49-415): 3.19e-93: 292: 18.14
+	Hs
		496706 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		121669 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		PSD11_HUMAN (20-385): 1.17e-81: 258: 14.63
+	Hs
		497525 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87