HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AGAP1 (Q9UPQ3)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP-1) (Centaurin-gamma-2) (Cnt-g2) (GTP-binding and GTPase-activating protein 1) (GGAP1)
Gene: AGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 857
+	Hs
		497458 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AGAP3_HUMAN (4-827): 0: 768: 72.46
+	Hs
		497044 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACAP2_HUMAN (308-854): 7.28e-132: 414: 16.55
+	Dm
		1342084 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CEG1A_DROME (4-815): 0: 594: 47.86
+	Mm
		88454 D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56		AGAP2_MOUSE (53-827): 0: 579: 52.95
+	Mm
		1112664 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		AGAP2_MOUSE (53-827): 0: 579: 52.95
+	Hs
		195781 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ASAP2_HUMAN (367-855): 2.92e-95: 322: 19.77
+	Hs
		497850 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		GIT1_HUMAN (616-848): 2.84e-73: 257: 31.58
+	Hs
		496764 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAB1A_HUMAN (72-257): 3.27e-72: 237: 24.35
+	Hs
		496708 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RAP1B_HUMAN (69-229): 7.97e-70: 230: 22.75
+	Mm
		497979 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		RAB1A_MOUSE (72-257): 3.27e-72: 237: 24.35
+	Hs
		1295178 ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94		Q9H4D1_HUMAN (376-855): 5.28e-87: 295: 16.17
+	Hs
		1050179 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		GIT2_HUMAN (616-823): 7.46e-74: 258: 33.33
+	Hs
		1377463 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		GIT1_HUMAN (616-848): 2.84e-73: 257: 31.58
+	Hs
		883603 ZN469_HUMAN (7-623): 9.52e-09: 61.2: 10.94		RIPK4_HUMAN (566-798): 1.5e-13: 76.7: 13.81