HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: COR2B (Q9UQ03)
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Gene: CORO2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 480
+	Hs
		497789 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COR1C_HUMAN (9-472): 1.92e-113: 344: 44.73
+	Hs
		496401 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COR1A_HUMAN (9-478): 1.38e-109: 334: 43.28
+	Hs
		497516 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COR1B_HUMAN (6-480): 9.58e-107: 327: 42.17
+	Hs
		1163311 MAGE1_HUMAN (222-587): 4.83e-09: 61.9: 16.22		CORO6_HUMAN (9-477): 7.19e-115: 348: 45.03
+	Hs
		497103 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RBBP7_HUMAN (82-167): 1.41e-12: 71.2: 20.43
+	Hs
		496923 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		RBBP4_HUMAN (83-167): 4.07e-12: 69.7: 19.57
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Hs
		654026 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		FBXW7_HUMAN (2-294): 2.8e-59: 209: 14.62
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Hs
		152678 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		FBXW7_HUMAN (2-294): 2.8e-59: 209: 14.62
+	Dm
		973546 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		Q9W3W1_DROME (15-469): 2.05e-71: 246: 25.44
+	Dm
		90207 CPN_DROME (345-756): 7.29e-11: 67.8: 11.17		D6W4T8_DROME (15-469): 1.18e-70: 245: 25.44
+	Hs
		1281391 PRR36_HUMAN (1-607): 1.27e-15: 83.6: 10.11		FBXW7_HUMAN (2-294): 2.8e-59: 209: 14.62
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (3-301): 2.48e-65: 215: 14.89
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (3-301): 2.48e-65: 215: 14.89
+	Hs
		1056932 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		SNR40_HUMAN (172-399): 4.86e-39: 146: 10.48
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (255-414): 5.36e-19: 89.6: 8.75
+	Ce
		557846 RPB1_CAEEL (82-426): 9.08e-11: 68: 14.12		LIN53_CAEEL (20-167): 9.52e-13: 71.6: 19.75