HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: AP3M1 (Q9Y2T2)
AP-3 complex subunit mu-1 (AP-3 adaptor complex mu3A subunit) (Adaptor-related protein complex 3 subunit mu-1) (Mu-adaptin 3A) (Mu3A-adaptin)
Gene: AP3M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1904115 - axon cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 418
+	Hs
		497548 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP1M1_HUMAN (2-418): 6.37e-162: 463: 26.73
+	Hs
		496626 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP3M2_HUMAN (1-418): 1.44e-152: 439: 84.21
+	Hs
		497422 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AP2M1_HUMAN (1-417): 9.68e-146: 423: 24.44
+	Rn
		581982 TAU_RAT (1-758): 4.86e-75: 260: 71.47		AP2M1_RAT (1-417): 9.68e-146: 423: 24.44
+	Rn
		94205 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		AP2M1_RAT (1-417): 9.68e-146: 423: 24.44
+	Mm
		498008 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		AP2M1_MOUSE (1-417): 9.68e-146: 423: 24.44
+	Hs
		654028 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		AP2M1_HUMAN (1-417): 9.68e-146: 423: 24.44
+	Dm
		248311 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		O62530_DROME (1-417): 1.93e-143: 417: 24.44
+	Hs
		203244 SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76		AP2M1_HUMAN (1-417): 9.68e-146: 423: 24.44
+	Hs
		496542 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		COPD_HUMAN (7-159): 1.26e-35: 139: 10.39