HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TR150 (Q9Y2W1)
Thyroid hormone receptor-associated protein 3 (BCLAF1 and THRAP3 family member 2) (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150)
Gene: THRAP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	26269332, 35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0016607 - nuclear speck
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 955
+	Hs
		497685 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		BCLF1_HUMAN (38-949): 3.55e-78: 276: 33.19
+	Hs
		1057033 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TR150_HUMAN (1-955): 9.81e-127: 408: 100.00
+	Hs
		496871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK2_HUMAN (47-877): 6.14e-50: 195: 12.46
+	Hs
		497818 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SRRM2_HUMAN (2-858): 2.43e-23: 109: 14.55
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (105-799): 3.29e-11: 70: 7.20
+	Rn
		562615 TAU_RAT (1-758): 4.86e-75: 260: 71.47		NFH_RAT (14-534): 2.55e-18: 92.7: 10.92
+	Rn
		94083 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		F1LRZ7_RAT (14-534): 2.54e-18: 92.7: 10.92
+	Hs
		1056827 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MDC1_HUMAN (2-649): 1.14e-11: 71.2: 8.49
+	Hs
		1056876 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MICA3_HUMAN (169-857): 2.66e-09: 63.4: 7.24
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (109-621): 2.93e-12: 73.5: 7.57
+	Ce
		136802 UNC89_CAEEL (4-459): 4.47e-21: 101: 12.37		UNC22_CAEEL (115-817): 2.1e-09: 63.9: 15.40
+	Dm
		54892 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		A1ZA72_DROME (136-802): 5.45e-11: 69.3: 13.52
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (105-876): 3.39e-12: 73.1: 9.68