HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0043005 - neuron projection
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 761
+	Hs
		1377463 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		1050179 PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Hs
		60284 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		POTEF_HUMAN (31-683): 7.43e-63: 230: 13.13
+	Hs
		497809 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AGAP1_HUMAN (2-223): 4.13e-57: 211: 32.89
+	Hs
		497458 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		AGAP3_HUMAN (2-223): 6.5e-55: 205: 34.22
+	Hs
		497044 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ACAP2_HUMAN (2-331): 3.4e-53: 199: 18.50
+	Hs
		195781 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ASAP2_HUMAN (2-506): 1.34e-50: 193: 15.20
+	Hs
		496939 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		496871 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52
+	Rn
		251021 TAU_RAT (1-758): 4.86e-75: 260: 71.47		ANK3_RAT (93-695): 5.51e-40: 161: 12.12
+	Rn
		94107 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		ANK3_RAT (93-695): 5.51e-40: 161: 12.12
+	Hs
		1056981 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TNKS2_HUMAN (135-556): 6.36e-46: 179: 10.94
+	Hs
		310053 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		TNKS1_HUMAN (60-480): 1.04e-37: 154: 12.78
+	Mm
		88454 D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112664 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Dm
		1342084 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		CEG1A_DROME (1-213): 6.24e-45: 176: 29.17
+	Dm
		1182373 Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96		Q7KU92_DROME (166-494): 1.31e-30: 132: 10.54
+	Mm
		292551 MYO15_MOUSE (50-503): 2.51e-11: 69.6: 13.00		INVS_MOUSE (133-498): 8.39e-27: 119: 11.83